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Treaty of Madrid (1526) : ウィキペディア英語版
Italian War of 1521–26

The Italian War of 1521–26, sometimes known as the Four Years' War,〔The name refers to the four years between the beginning of hostilities in 1521 and the Battle of Pavia in 1525, although the war did not formally end until 1526.〕 was a part of the Italian Wars. The war pitted Francis I of France and the Republic of Venice against the Holy Roman Emperor Charles V, Henry VIII of England, and the Papal States. The conflict arose from animosity over the election of Charles as Emperor in 1519–20 and from Pope Leo X's need to ally with Charles against Martin Luther.
The war broke out across Western Europe late in 1521, when a French–Navarrese expedition attempted to reconquer Navarre while a French army invaded the Low Countries. A Spanish army drove the Navarrese forces back into the Pyrenees, and other Imperial forces attacked northern France, where they were stopped in turn.
The Pope, the Emperor, and Henry VIII then signed a formal alliance against France, and hostilities resumed on the Italian Peninsula; but, with the attention of both Francis and Charles focused on the battleground in northeast France, the conflict in Italy became something of a sideshow.〔Mallett and Shaw, ''The Italian Wars'', 140.〕 At the Battle of Bicocca on 27 April 1522, Imperial and Papal forces defeated the French, driving them from Lombardy.〔Mallett and Shaw, ''The Italian Wars'', 142–43.〕 Following the battle, fighting again spilled onto French soil, while Venice made a separate peace. The English invaded France in 1523, while Charles de Bourbon, alienated by Francis's attempts to seize his inheritance, betrayed Francis and allied himself with the Emperor. A French attempt to regain Lombardy in 1524 failed and provided Bourbon with an opportunity to invade Provence at the head of a Spanish army.
Francis himself led a second attack on Milan in 1525. While he was initially successful in driving back the Spanish and Imperial forces, his disastrous defeat at the Battle of Pavia, where he was captured and many of his chief nobles were killed, led to the end of the war. With Francis imprisoned in Spain, a series of diplomatic maneuvers centered on his release ensued, including a special French mission sent by Francis' mother Louise of Savoy to the court of Suleiman the Magnificent that would result in an Ottoman ultimatum to Charles—an unprecedented alignment between Christian and Muslim monarchs that would cause a scandal in the Christian world and lay the foundation for the Franco-Ottoman alliance. Suleiman used the opportunity to invade Hungary in the summer of 1526, defeating Charles' allies at the Battle of Mohács; but, despite these efforts, Francis would sign the Treaty of Madrid, surrendering his claims to Italy, Flanders, and Burgundy. Only a few weeks after his release, however, he repudiated the terms of the treaty, starting the War of the League of Cognac. Although the Italian Wars would continue for another three decades, they would end with France having failed to regain any substantial territories in Italy.
== Prelude ==
By 1518, the peace that had prevailed in Europe after the Battle of Marignano was beginning to crumble. The major powers (France, England, Spain, and the Holy Roman Empire) were outwardly friendly, pledging by the Treaty of London to come to the aid of any of the signatories that was attacked and to combine against any nation that broke the peace. They were divided, however, on the question of the Imperial succession. The Holy Roman Emperor, Maximilian I, intending for a Habsburg to succeed him, began to campaign on behalf of Charles of Spain, while Francis put himself forward as an alternate candidate. At the same time, the Papacy and the Holy Roman Empire were forced to deal with the rising influence of Martin Luther, who found support among some Imperial nobles, while Francis was faced with Cardinal Thomas Wolsey, who interposed himself into the quarrels of the continent in an attempt to increase both England's influence and his own.
Maximilian's death in 1519 brought the Imperial election to the forefront of European politics. Pope Leo X, threatened by the presence of Spanish troops a mere forty miles from the Vatican, supported the French candidacy. The prince-electors themselves, with the exception of Frederick of Saxony, who refused to countenance the campaigning, promised their support to both candidates at once. Before his death, Maximilian had already promised sums of 500,000 florins to the Electors in exchange for their votes, but Francis offered up to three million, and Charles retaliated by borrowing vast sums from the Fuggers. The final outcome, however, was not determined by the exorbitant bribes, which included Leo promising to make the Archbishop of Mainz his permanent legate. The general outrage of the populace at the idea of a French Emperor gave the Electors pause, and when Charles put an army in the field near Frankfurt, where they were meeting, the Electors obligingly voted for him.〔Guicciardini, ''History of Italy'', 316–318.〕 He was crowned Holy Roman Emperor on 23 October 1520, by which point he already controlled both the Spanish crown and the hereditary Burgundian lands in the Low Countries.
Cardinal Wolsey, hoping to increase Henry VIII's influence on the continent, offered the services of England as a mediator for the various disputes between Francis and Charles. Henry and Francis staged an extravagant meeting at the Field of the Cloth of Gold. Immediately afterwards, Wolsey entertained Charles in Calais. Following the meetings, Wolsey, concerned mainly with improving his own stature in preparation for the next papal conclave, proceeded to stage a hollow arbitration conference at Calais, which lasted until April 1522 to no practical effect.
In December, the French began to plan for war. Francis did not wish to openly attack Charles because Henry had announced his intention to intervene against the first party to break the tenuous peace. Instead, he turned to more covert support for incursions into Imperial and Spanish territory. One attack would be made on the Meuse River, under the leadership of Robert de la Marck. Simultaneously, a French-Navarrese army would advance through Navarre after reconquering St-Jean-Pied-de-Port.〔Monreal and Jimeno, ''Conquista'', 67.〕 The expedition was nominally led by the 18-year-old Navarrese king Henry d'Albret, whose kingdom had been invaded by Ferdinand II of Aragon in 1512, but the army was effectively commanded by André de Foix and funded and equipped by the French.〔Blockmans, ''Emperor Charles V'', 51–52.〕 The French designs quickly proved flawed as the intervention of Henry of Nassau drove back the Meuse offensive; and although de Foix was initially successful in seizing Pamplona, he was driven from Navarre after being defeated at the Battle of Esquiroz on 30 June 1521.〔Oman, ''Art of War'', 173–174.〕
Charles was meanwhile preoccupied with the issue of Martin Luther, whom he confronted at the Diet of Worms in March 1521. The Emperor viewed Catholicism as a natural way of binding the diverse principalities of the Holy Roman Empire to him. Since Pope Leo X, for his part, was unwilling to tolerate such open defiance of his own authority, he and the Emperor were forced to support one another against Luther, who was now backed by Frederick of Saxony and Franz von Sickingen. On 25 May 1521, Charles and Cardinal Girolamo Aleandro, the Papal nuncio, proclaimed the Edict of Worms against Luther. Simultaneously, the Emperor promised the Pope the restoration of Parma and Piacenza to the Medici and of Milan to the Sforza. Leo, needing the Imperial mandate for his campaign against what he viewed as a dangerous heresy, promised to assist in expelling the French from Lombardy, leaving Francis with only the Republic of Venice for an ally.

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